Trisulfone for rabbits: instructions for use of the drug

Rabbit breeding is a laborious and painstaking process., which requires a lot of responsibility and attention.

These animals, despite their high productivity, are often exposed to diseases. Often, infections lead to the death of the entire livestock rabbit family.

Therefore, in order to avoid this, it is important to provide timely therapeutic and preventive measures using various drugs.

Often for the treatment and prevention of infectious lesions in rabbits the drug Trisulfone is used.

How to use this medicine correctly, and for what diseases to use, you can find out from the detailed instructions for this remedy.

Trisulfone: instructions for use

Trisulfone is a drug, which has a preventive and curative effect. It quickly removes many types of infections and viruses.

This medicine is widely used in the veterinary field. for the treatment of rabbits and poultry. This agent is included in the group of drugs of a combined chemotherapeutic type, which have a wide area of ​​effect.

During admission, the constituent components have a detrimental effect on infectious agents, destroy the membrane, stop development and lead to their death.

In addition, he provides effective impact during preventive treatment after suffering infectious diseases.

Release form of the drug

Available in the form of a white powder with a free-flowing structure... Products of this type are odorless and soluble in water.

The medicine in this form is contained in packages of 1 kilogram... The bags are hermetically sealed and made of foil with a laminated structure.

Sometimes on sale you can find powder packed in containers made of plastic material.

Trisulfone is found in veterinary pharmacies as a suspension... The structure of the suspension is liquid, medium consistency. A mixture of light or cream color.

It is sold in brown glass base bottles, the volume of the bottles is 100 ml... It is found in containers from a plastic base with a volume of up to 1 liter.

Powder medicine

The preparation in powder form is used for internal or oral use. It is used for both treatment and prevention of infectious diseases and diseases of the digestive system, nervous system, respiratory system and genitourinary system.

1 gram of this product includes the following components:

  • 40 mg of the main component - sulfamonomethoxin;
  • 20 mg of an additional component - lactose monohydrate.

It is worth noting that despite the fact that the instructions indicate a shelf life of up to three years, after the package with the powder is opened, the product is stored for no more than a month.

After this time, the active ingredient of the drug completely has its own properties.

As a suspension

The suspension is applied for internal or oral ingestion. It is also used for the treatment and preventive measures for infectious lesions and pathologies of the digestive system, respiratory system, nervous system, and genitourinary system.

1 gram of funds in this form contains the following components:

  • 40 grams of the main component - sulfamonomethoxin in the form of sodium salt;
  • 8 grams of trimethoprim.

In addition to these components, additional auxiliary components. Ancillary components include the following components:

  • cellulose in microcrystalline form;
  • sodium carboxymethyl cellulose;
  • twin 80;
  • sorbitol solution 70%;
  • sugar sodium;
  • benzyl alcohol;
  • simethicone;
  • demineralized water.

The product is stored closed for three years. After opening, the medicine is used for 2 months, but not more.

After this period, the main constituent component loses its effect.

Pharmachologic effect

Trisulfone belongs to the group of agents with complex antibacterial action... The active component of this agent, sulfamonomethoxin, has a wide area of ​​effect.

During exposure, this substance has a damaging effect on the following microbes:

  • if;
  • salmonella;
  • staphylococci;
  • streptococci;
  • shigella;
  • on other bacteria of the simplest type - Coccidia and Toxoplasma gondi.

In terms of structure, sulfamonomethoxin has similar properties with the structure of para-aminobenzoic acid. It causes a disruption in the synthesis of dihydrofolic acid in cells of the bacterial type, as a result of which it leads to the prevention of the entry of para-aminobenzoic acid into the molecule of the bacterial cell.

The second active ingredient, trimethoprim, causes an increase in the influence of sulfamonomethoxin, which ultimately causes a violation of the reduction of dihydrofolic acid to tetrahydrofolic acid.

During the combined action, there is violation of the synthesis of folic acid in two successive stages.

This causes disruption of nucleotide synthesis, which determines the synergistic bactericidal effect of the complex of sulfamonomethoxin and trimethoprim.

Absorption and excretion

Active ingredients - sulfamonomethoxin and thimethoprim have fast and good absorption of the gastrointestinal tract.

These components enter all organs and tissues of the body, where they maintain antibacterial concentrations for a day.

The excretion of these components is carried out by the kidneys along with urine. and bile. They are displayed unchanged.


Trisulfone is used during treatment and prevention diseases of an infectious nature. Veterinarians prescribe this drug to rabbits to treat the following diseases:

  • salmonellosis;
  • pasteurellosis;
  • coccidiosis;
  • colicbacteriosis;
  • staphylococcus;
  • diseases of the digestive system;
  • respiratory tract lesions;
  • pathologies of the genitourinary system;
  • rhinitis of an infectious nature.

How to apply?

For babies

Trisulfone is used for cubs to treat and prevent infectious lesions., as well as pathologies of the digestive system, nervous system, respiratory organs of the genitourinary system.

It is important to start using this remedy in the early stages of the disease, otherwise the entire rabbit population may die.

The main thing is to observe the dosage correctly. and the rules for using the drug:

  1. Trisulfone is given orally to rabbits in a group way, depending on the type of drug.
  2. When using the product in the form of a powder, it is added in a dosage of 8 grams of powder per 1 liter of water.
  3. Then the rabbits are fed with this solution during the day.
  4. The powder can be added to feed mixtures.
  5. Powder treatment lasts 5 days.
  6. If a suspension is given, then its reception nuances differ. In case of coccidiosis, 1 ml of suspension is added to 1 liter of water. The course of treatment is from 3 to 5 days.
  7. For other pathologies and infections - 1 ml of suspension is given for 32 kilograms of animal body weight. The course of treatment lasts from 3 to 5 days.

Treatment of young rabbits with Trisulfone begins at the age of 1 month and more.

Attention: for the treatment to be effective and led to a positive result, it is necessary to strictly follow the rules for taking the medicine. It is not recommended to skip the dose, the regime of keeping animals should be observed.

For adults

For adults, Trisulfone is used for the treatment and prevention of many infectious lesions, in case of malfunction and damage to the digestive, nervous, respiratory, and genitourinary systems.

If animals are infected coccidiosis, salmonellosis, pasteurellosis, colicbacteriosis, staphylococcus, it is important to identify the disease at an early stage. Otherwise, all rabbit offspring may die.

For this reason, rabbits are closely monitored, their behavior and appearance. In addition, they must provide appropriate care and comply with the necessary conditions for their maintenance.

How to use Trisulfone correctly:

  1. As with the young, the remedy is given in a group way. It is taken orally.
  2. If a powder is used for treatment, then 8 grams of powder is added to 1 liter of water. Everything is thoroughly mixed.
  3. Individuals are drunk with a solution with a medicine during the day. The treatment lasts up to 5 days.
  4. During coccidiosis, a suspension is given - 1 ml of suspension is diluted in 1 liter of water. Affected animals are given to drink with this solution. Treatment is 3 to 5 days.
  5. For other infectious diseases, 1 ml of suspension is given per 32 kilograms of rabbit body weight. The course of treatment is 3 to 5 days.

Please note that the meat of the affected animal is eaten only 10 days after the application of Trisulfone.

If the slaughter was performed earlier, then the meat of this rabbit can be used to feed animals that eat fresh meat.

Dosage and side effects

In general, if the rules for taking the medicine and its dosages are observed, side effects do not occur. This product belongs to the class of low-hazard products.

Sometimes animals may have a hypersensitivity to the constituent components of Trisulfone.


It is not recommended to use Trisulfone for the following indications:

  1. Animals that are hypersensitive to the active ingredients of the drug - sulfamonomethoxin and trimetroprim.
  2. Has a dangerous effect on individuals with kidney problems.
  3. It is not recommended to give to pregnant women and during lactation.
  4. It is not advisable to combine the agent with local anesthetics.


The cost of the drug Trisulfone in powder form for 1 packet volume of 1 kilogram is about 1700-2000 rubles.

Price for 1 bottle of suspension a volume of 100 ml starts from 360 rubles and reaches 400 rubles.

Reviews of rabbit breeders

Sergey: “I have been breeding rabbits for a long time. These animals are highly fertile, in 1 year one healthy female as a whole brings up to 70-80 rabbits. And their meat is of high value. But all would be fine, only these animals are often infected with various infections. In the first year, unknowingly, as a result of an infectious lesion, he lost almost 50 heads of offspring in a month. But over time, I gained experience and now I know that it is imperative to carry out prevention. Often, when the first symptoms of infectious diseases appear, they immediately begin to water the rabbits with a solution of Trisulfone. I mainly use it in powder form. It helps to cure many diseases well and, most importantly, quickly! I recommend to everyone!"

Alexander: “When I first encountered coccidiosis and salmonellosis in rabbits, I was immediately scared and did not know how to treat them. A well-known person who has been breeding rabbits for a long time immediately advised using the drug Trisulfone. I purchased the drug in the form of a suspension and began to water the rabbits according to the instructions. The result exceeded all my expectations. In 5 days, all individuals were safely cured and all symptoms of diseases completely disappeared! "

Oleg: “I have been breeding rabbits for 10 years and of course I have to deal with various infectious diseases. These animals are often exposed to many infections, which, if not treated during treatment, can be fatal. For their treatment, I use the drug Trisulfone. This remedy has an effective effect and is capable of curing the disease in a short period. I use it in the form of a powder and a suspension, according to the mode of action, these forms are the same. In addition to treatment, all care rules are followed and the place where rabbits are kept is kept clean! "

The use of the drug Trisulfone for the treatment of rabbits should be mandatory for the treatment and prevention of infectious diseases.

This is due to its high efficiency and fast action on infectious agents.

The main thing is to follow the rules of admission of this drug and its dosage. In addition, do not forget about proper care for your offspring, a balanced diet and the use of vitamins to strengthen their immune system.

White free-flowing preparation powder for oral administration. Let's well dissolve in drinking water. Release form laminated foil bags, packing of 1 kg. Each package has instructions for use in Russian. Other packaging and dosage forms in the form of tablets, ready-made solutions, etc., are not declared by the manufacturer for Russia.

Trisulfone for rabbits is a complex antibacterial drug, contains sulfonamide and an antibiotic, mutually reinforcing each other's action. The drug is active against the group of Escherichia coli, Salmonella, Staphylococcus, Streptococcus, Shigella. Proved activity against protozoan parasites (coccidia, toxoplasma). Sulfamonomethoxin in the composition of the drug disrupts the synthesis of dihydrofolic acid, prevents its participation in the metabolic processes of the microbe. Trimethoprim enhances the effect of sulfonamide. The drug is well absorbed into organs and tissues, creates therapeutic concentrations that are maintained throughout the day. They are excreted from the body with bile in the feces, and also in the urine.


The combination of several active ingredients expands the spectrum of action of the drug on pathogenic microflora. The active ingredients are trimethoprim and the sodium salt of sulfamonomethoxin. To eliminate side effects on the body, enhance the antimicrobial action, use the following auxiliary ingredients:

  • Microcrystalline cellulose.
  • Benzyl alcohol.
  • Croscarmellose sodium.
  • Polysorbate.
  • Sodium saccharinate.
  • Sorbitol.

When and how to use?

Trisulfone for rabbits is administered orally in a group manner, depending on the form of drug release. So, in the form of a powder, the agent is given at the rate of 8 grams per 1 liter of water. During treatment, rabbits can receive both water with the drug and food. As for the suspension, it is given in different doses in the treatment of different types of diseases.

  • For coccidiosis - 1 ml per 1 liter of water, give within 3-5 days
  • For other infectious diseases - 1 ml per 32 kilograms of rabbit weight, also give 3-5 days.

For greater effectiveness, the remedy is not recommended to skip the next dose of the drug, you need to follow the rabbit regimen.


Trisulfone belongs to low-hazard types of drugs and, according to GOST, belongs to the 4th class. This means that the drug does not cause side effects and does not give any complications in the recommended dose. However, there are still caveats. So, for example, due to the fact that the drug is excreted through urine and bile, it is worth giving it with caution to rabbits with impaired kidney and liver function. It is not recommended to combine with vitamins of group B, for example, with folic acid, choline, as well as together with procaine and other local anesthetics.

Indications for use

The drug in the form of a suspension and powder is indicated for the treatment of diseases of the respiratory and urinary tract, digestion, secondary infections and other pathologiescaused by microorganisms sensitive to the active ingredients of the drug, including:

  • coccidiosis, salmonellosis, colibacillosis, pasteurellosis, poultry staphylococcosis
  • rhinitis, pleuropneumonia, salmonellosis, pig colibacillosis
  • abscesses, colisepticemia, bronchopneumonia, polyarthritis, pasteurellosis, salmonellosis of young cattle (cattle).

Trisulfone in powder form is also prescribed to rabbits with pasteurellosis, colibacillosis, staphylococcosis, salmonellosis.

Trisulfone for chickens instruction

Trisulfon powder (1 kg)

Order Trisulfon powder (1 kg)

Instructions for use of the drug Trisulfon powder (1 kg)

General information
Trisulfone is a complex antibacterial drug in the form of a powder for oral administration, containing in 1 g of active ingredients 40 mg of sulfamonomethoxin in the form of sodium salt and 20 mg of trimethoprim, and lactose as an auxiliary substance.
Trisulfone in appearance is a white, free-flowing, odorless powder, soluble in water.
The drug is produced in the form of a powder for oral administration in hermetically sealed laminated foil bags of 100 g and 1 kg.
Each package is marked with the name, purpose and method of application of the drug, the name and content of active ingredients, the name of the manufacturing organization and its address, the inscription "For animals", the date of manufacture, batch number, expiration date, storage conditions and supplied with instructions for use ...

Pharmacological properties
The active ingredients of Trisulfone block the metabolism in a sensitive microbial cell and thus interfere with the synthesis of nucleic acids. Sulfamonomethoxin, being a competitor to para-aminobenzoic acid, inhibits the synthesis of functional folic acid. Trimethoprim blocks the enzyme dihydrofolate reductase, which activates folic acid. With the combined action, the synthesis of folic acid is disrupted in two successive stages, which leads to a violation of the synthesis of nucleotides and causes a synergistic bactericidal effect of the combination of sulfamonomethoxin and trimethoprim.
Trisulfone has a broad antibacterial spectrum of action against most gram-positive and gram-negative microorganisms, incl. staphylococci, streptococci, pasteurella, escherichia and salmonella.
The active ingredients of Trisulfone are well and quickly absorbed from the gastrointestinal tract and penetrate into all organs and tissues of the body, where they create antibacterial concentrations for 24 hours.
The active substances of Trisulfone are excreted from the body mainly with urine and bile.
Trisulfone is of little toxicity to warm-blooded animals; in recommended doses, it does not cause side effects and complications.

Application procedure
Trisulfone is used in farm animals, including poultry, for the treatment of diseases caused by microorganisms sensitive to the combination of sulfamonomethoxin and trimethoprim:
calves, kids, lambs - with colibacillosis, salmonellosis, pasteurellosis, bronchopneumonia, abscesses caused by staphylococci, polyarthritis caused by streptococci
pigs - with colibacillosis, atrophic rhinitis, salmonellosis, pasteurellosis, hemophilic pleuropneumonia
poultry - with pasteurellosis, colibacillosis, salmonellosis, staphylococcosis
rabbits - with pasteurellosis, staphylococcosis, colibacillosis, salmonellosis.

Trisulfone for calves, kids, lambs, pigs is administered orally in a mixture with feed in a daily dose of 10 g of the drug per 40 kg of animal body weight. The medicine is given to birds and rabbits with drinking water in the following daily doses:
poultry - 200 g of Trisulfone per 100 l of water
rabbits - 8 g of Trisulfone per 1 liter of water.

The duration of treatment is 5 days. When giving a medicinal product with drinking water, the medicinal solution is prepared directly on the day of its use. During the treatment period, birds and rabbits should receive only water containing Trisulfone.
Side effects and unwanted interactions are unknown, with the exception of cases of individual hypersensitivity to the components of the drug.
It is forbidden to use Trisulfone in laying hens, as well as animals with impaired renal function.
Slaughter of animals and poultry for meat is allowed no earlier than 10 days after the last administration of Trisulfone. The meat of animals that were forcedly killed earlier than the established date can be used for feeding carnivores.

Personal prevention measures
It is forbidden to use the medicinal product after the expiration date.
Store the medicinal product out of the reach of children and animals.
Do not drink, eat or smoke while working with the medicinal product.
All work with the drug is recommended to be carried out using personal protective equipment (rubber gloves, goggles, respirator or face shield).
Do not use empty medicine containers for household needs. Store empty medicine containers in specially designated places.

Store the medicinal product with caution (list B), in its original packaging, in a dry, dark place at a temperature of 0 to 25 ° C.

The shelf life of the medicinal product under the specified storage conditions is 3 years from the date of manufacture. After opening the original packaging, it is recommended to store the medicinal product in hermetically sealed containers and use it within no more than 30 days.

Unit of issue of goods: 1 bag 1 kg

What to do for prevention

The best way to avoid a runny nose - these are the right conditions for keeping pets, especially in winter. A warm room, no drafts, no dampness, vitamins and a varied diet.

As special preventive measures biomycin is added to the food of rabbits (0.5 grams per day for 1 rabbit)... Dill, mint, chamomile, wormwood, and basil also have antiviral effects.

Summing up, it should be emphasized that preventing rhinitis in pets is much easier than treating it later.

Moreover, practice knows a lot of examples when even antibiotics do not help the complete recovery of animals.

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